Research Area Research Subjects Overview of Research

Our research interests focus on bioanalytical chemistry based on the advanced design and synthesis of chemical probes that target significant biomarkers such as non-coding RNA and extracellular vesicles. We have created novel probes based on peptide nucleic acids, peptides, small organic molecules, or DNA-based aptamers, and have developed a highly sensitive and selective detection or imaging methods for biological research and drug discovery. Our recent progress includes the development of triplex-forming peptide nucleic acid for fluorescence sensing of double-stranded RNA, fluorescent probes for siRNA delivery imaging in living cells, and fluorescent ligands for mircoRNA detection. By providing such chemical probe-based bioanalytical methods, we are trying to contribute to the further development of life science.

Selected Publications

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